are lean and normal weight patients with polycystic ovarian syndrome at risk of preeclampsia?

نویسندگان

bibi shahnaz aali

seyed adel mahdi

nouzar makhaee

shiva soboutipour

چکیده

background: we examined whether pregnant women with preeclampsia have an increased rate of pre-pregnancy polycystic ovary syndrome (pcos). this study also evaluated whether the association, if any, was a result of preeclampsia and its relationship to pcos or dependent upon concurrent obesity. materials and methods: in this study, 75 preeclampsia cases and 225 normotensive pregnant controls, matched for age and gravidity, were enrolled. a confirmation of pre-pregnancy pcos was ascertained by recording medical history, along with a physical examination directed for signs and symptoms of pcos, an ultrasound report of polycystic ovaries and laboratory tests which confirmed hyperandrogenism prior to pregnancy. body mass index (bmi) was calculated for each patient. participants were classified into two categories: lean/normal and obese according to a bmi <25 or greater than 25.1, respectively. chi-square, student t test, fisher-exact and mann-whitney tests were used to assess the differences between the groups in addition to the relationship between preeclampsia and pcos. p values less than 0.05 were considered significant. results: age, gravidity and parity were not significantly different between cases and controls. however, a significant difference was found in gestational age and bmi between the groups. additionally, preeclamptic patients more frequently suffered from pre-pregnancy pcos than controls and a significant relationship was found between preeclampsia and previous pcos, even amongst lean/normal weight patients. conclusion: this study provides convincing evidence that a pre-pregnancy diagnosis of pcos could predispose the patient to preeclampsia, regardless of a concomitant obesity risk factor.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Are Lean and Normal Weight Patients with Polycystic Ovarian Syndrome at Risk of Preeclampsia?

Background We examined whether pregnant women with preeclampsia have an increased rate of pre-pregnancy polycystic ovary syndrome (PCOS). This study also evaluated whether the association, if any, was a result of preeclampsia and its relationship to PCOS or dependent upon concurrent obesity. MaterialsAndMethods In this study, 75 preeclampsia cases and 225 normotensive pregnant controls, matched...

متن کامل

Comparison of 25-hydroxyvitamin D and Calcium Levels between Polycystic Ovarian Syndrome and Normal Women

Background Given the relationship of vitamin D deficiency with insulin resistance syndrome as the component of polycystic ovary syndrome (PCOS), the main aim of this study was to compare serum level of 25- hydroxyvitamin D [25(OH)D] between PCOS patients and normal individuals. MaterialsAndMethods A cross sectional study was conducted to compare 25(OH)D level between117 normal and 125 untreated...

متن کامل

are women with polycystic ovarian syndrome at a high risk of non-alcoholic fatty liver disease; a meta-analysis

conclusions according to the results of this meta-analysis, there was a high risk of nafld in women with pcos. we suggest evaluating patients with pcos regarding nafld. results we finally included seven eligible studies. according to chi-squared test, there was a significant heterogeneity (73.6%) between studies (p = 0.001). nafld prevalence was significantly higher in patients with pcos compar...

متن کامل

Birth weight in offspring of mothers with polycystic ovarian syndrome.

BACKGROUND A relationship between reduced fetal growth and the polycystic ovary syndrome (PCOS) has been proposed in girls with PCOS. However, the birth weight in the offspring of PCOS mothers has not been systematically investigated. The aim of this study was to establish the birth weight of newborns of mothers with PCOS and to compare it with a control group of newborns of normal women matche...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
international journal of fertility and sterility

جلد ۴، شماره ۱، صفحات ۵-۸

کلمات کلیدی

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023